Week 16 NFL Picks, Odds, Betting Analysis For Every Game

It’s the holiday season! So Santa Claus is here to give you against-the-spread picks for every Week 16 game. But first, here is how we did last week:

Week 15 record: 9-7
Season record: 117-106-1

Thursday, December 23, 2021

San Francisco 49ers (-3.5) at Tennessee Titans

Andre’s Pick: 49ers.

Saturday, December 25, 2021

Cleveland Browns at Green Bay Packers (-7)

Andre’s Pick: Browns.

Indianapolis Colts at Arizona Cardinals (-1)

Andre’s Pick: Cardinals

Sunday, December 26, 2021

NYG at PHI (-10): PHI
LAR (-3.5) at MIN: LAR
BUF at NE (-1): BUF
TB (-9.5)at CAR: TB
JAX at NYJ (-1.5): JAX
DET at ATL (-6): DET
LAC (-10) at HOU: LAC
BAL at CIN (-7): CIN
CHI at SEA (-6.5): SEA
DEN (-1) AT LV: LV
PIT AT KC (-10): KC
MIA (-2.5) AT NO: MIA

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